{"id":6024,"date":"2023-07-20T16:04:08","date_gmt":"2023-07-20T15:04:08","guid":{"rendered":"https:\/\/upbeat-bassi.138-201-129-95.plesk.page\/informazioni-sulla-ftd\/"},"modified":"2025-04-08T15:30:22","modified_gmt":"2025-04-08T14:30:22","slug":"informazioni-sulla-ftd","status":"publish","type":"page","link":"https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/it\/informazioni-sulla-ftd\/","title":{"rendered":"Informazioni sulla FTD"},"content":{"rendered":"

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Informazioni sulla FTD<\/h1>\n

La demenza frontotemporale (FTD) \u00e8 una forma devastante di demenza a esordio precoce che varia in ciascun individuo. I sintomi della DFT possono includere cambiamenti della personalit\u00e0 o comportamenti non caratteristici, perdita progressiva del linguaggio, perdita della funzione esecutiva e delle capacit\u00e0 cognitive, apatia e ridotta mobilit\u00e0.\u00b9\u207b\u00b3<\/span> La FTD causa una sostanziale riduzione dell\u2019aspettativa di vita e in media le persone affette da FTD muoiono a 3-13 anni dalla diagnosi.\u2074\u207b\u2077<\/span> Si tratta di una malattia gravemente invalidante, con i\/le pazienti che riferiscono difficolt\u00e0 e problemi nello svolgimento delle attivit\u00e0 quotidiane, anche a stadi lievi e moderati della malattia.\u2078<\/span><\/p>\n

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La FTD \u00e8 una delle cause principali di demenza giovanile (o precoce) nei soggetti di et\u00e0 inferiore a 65 anni.\u2079<\/span> Si stima che negli Stati Uniti vi siano circa 20.000-30.000 pazienti affetti\/e da FTD\u00b2<\/span> e ogni anno in Europa vengono diagnosticati pi\u00f9 di 12.000 nuovi casi di FTD.\u00b9\u2070 <\/span> La prevalenza e l\u2019incidenza della FTD sono probabilmente sottostimate a causa della difficolt\u00e0 di identificazione e diagnosi della FTD.\u00b2,\u2075<\/span><\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”||40px||false|false” border_width_bottom=”2px” border_color_bottom=”#26B2B6″ global_colors_info=”{}”][et_pb_blurb image=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2024\/11\/AviadoBio-icon-FTD-7.png” alt=”Aviadobio” icon_placement=”left” image_icon_width=”100px” content_max_width=”100%” icon_placement_tablet=”” icon_placement_phone=”top” icon_placement_last_edited=”on|phone” _builder_version=”4.24.2″ _module_preset=”default” header_text_color=”#ffffff” header_font_size=”26px” header_letter_spacing=”2px” body_text_color=”#43464F” body_font_size=”20px” body_link_font=”SweetSans Light||||||||” body_link_text_color=”#26B2B6″ body_link_font_size=”18px” body_link_letter_spacing=”3px” image_icon_custom_padding_tablet=”” image_icon_custom_padding_phone=”” image_icon_custom_padding_last_edited=”on|phone” custom_css_blurb_image=”padding-right:20px;||” border_color_all_image=”#26B2B6″ border_width_all_image_tablet=”” border_width_all_image_phone=”” border_width_all_image_last_edited=”on|phone” image_max_width=”100px” global_colors_info=”{}” body_link_text_color__hover_enabled=”off|desktop” body_link_text_color__hover=”#ffffff”]<\/p>\n

A causa dell’esordio tipicamente precoce della FTD, essa ha effetti dannosi significativi sulle relazioni, sulla vita sociale, sul funzionamento occupazionale, sullo stato finanziario e sulla qualit\u00e0 della vita.\u2078,\u2079<\/span> La maggior parte dei servizi di assistenza sanitaria e sociale per la demenza \u00e8 personalizzata per gli anziani e i\/le pazienti con malattia di Alzheimer (Alzheimer’s disease, AD) e quindi spesso non soddisfa le esigenze dei\/lle pazienti pi\u00f9 giovani affetti da FTD e dei loro accompagnatori familiari o professionali.\u2075<\/span><\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” custom_padding_last_edited=”on|tablet” _builder_version=”4.24.2″ _module_preset=”default” custom_margin=”||||false|false” custom_padding=”0px||50px||false|false” custom_padding_tablet=”0px||30px||false|false” custom_padding_phone=”” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”||40px||false|false” border_width_bottom=”2px” border_color_bottom=”#26B2B6″ global_colors_info=”{}”][et_pb_blurb image=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2023\/07\/AviadoBio-icon-FTD-3.png” alt=”Aviadobio” icon_placement=”left” image_icon_width=”100px” content_max_width=”100%” icon_placement_tablet=”” icon_placement_phone=”top” icon_placement_last_edited=”on|phone” _builder_version=”4.24.2″ _module_preset=”default” header_text_color=”#ffffff” header_font_size=”26px” header_letter_spacing=”2px” body_text_color=”#43464F” body_font_size=”20px” body_link_font=”SweetSans Light||||||||” body_link_text_color=”#26B2B6″ body_link_font_size=”18px” body_link_letter_spacing=”3px” image_icon_custom_padding_tablet=”” image_icon_custom_padding_phone=”” image_icon_custom_padding_last_edited=”on|phone” custom_css_blurb_image=”padding-right:20px;||” border_color_all_image=”#26B2B6″ border_width_all_image_tablet=”” border_width_all_image_phone=”” border_width_all_image_last_edited=”on|phone” image_max_width=”100px” global_colors_info=”{}” body_link_text_color__hover_enabled=”off|desktop” body_link_text_color__hover=”#ffffff”]La FTD pu\u00f2 essere suddivisa in FTD familiare e sporadica.\u00b9\u00b9<\/span> La DFT sporadica \u00e8 pi\u00f9 comune.\u00b9\u00b9<\/span> Tuttavia, la FTD \u00e8 altamente ereditaria e una forte anamnesi familiare si riscontra in circa il 30-50% di tutti\/e i\/le pazienti affetti\/e da FTD.\u2075,\u00b9\u00b9,\u00b9\u00b2<\/span> Le mutazioni nella progranulina (GRN) rappresentano circa il 10% di tutti i casi di FTD e circa il 22% dei casi familiari di FTD.\u00b9\u00b2<\/span>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”||40px||false|false” border_width_bottom=”2px” border_color_bottom=”#26B2B6″ global_colors_info=”{}”][et_pb_blurb image=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2023\/07\/AviadoBio-icon-FTD-4.png” alt=”Aviadobio” icon_placement=”left” image_icon_width=”100px” content_max_width=”100%” icon_placement_tablet=”” icon_placement_phone=”top” icon_placement_last_edited=”on|phone” _builder_version=”4.24.2″ _module_preset=”default” header_text_color=”#ffffff” header_font_size=”26px” header_letter_spacing=”2px” body_text_color=”#43464F” body_font_size=”20px” body_link_font=”SweetSans Light||||||||” body_link_text_color=”#26B2B6″ body_link_font_size=”18px” body_link_letter_spacing=”3px” image_icon_custom_padding_tablet=”” image_icon_custom_padding_phone=”” image_icon_custom_padding_last_edited=”on|phone” custom_css_blurb_image=”padding-right:20px;||” border_color_all_image=”#26B2B6″ border_width_all_image_tablet=”” border_width_all_image_phone=”” border_width_all_image_last_edited=”on|phone” image_max_width=”100px” global_colors_info=”{}” body_link_text_color__hover_enabled=”off|desktop” body_link_text_color__hover=”#ffffff”]I test genetici sono diventati pi\u00f9 comuni con l\u2019aumento delle conoscenze sulla FTD genetica.\u2074<\/span> Tuttavia, vi \u00e8 ancora una necessit\u00e0 urgente di incorporare la consulenza genetica e i test appropriati nelle cure standard dei\/lle pazienti affetti\/e da FTD.\u2074,\u2078<\/span> L\u2019accesso e il ricorso a una consulenza genetica e di test appropriati e tempestivi devono essere migliorati per tutti\/e i\/le pazienti affetti\/e da FTD. Sebbene attualmente non vi siano trattamenti modificanti la malattia approvati per la FTD, capire se la FTD sia causata da una mutazione genetica pu\u00f2 consentire ai medici di stabilire se i\/le pazienti sono idonei\/e a una sperimentazione clinica.[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” disabled_on=”on|on|on” _builder_version=”4.24.2″ _module_preset=”default” custom_margin=”||||false|false” custom_padding=”0px||50px||false|false” disabled=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”||40px||false|false” border_width_bottom=”2px” border_color_bottom=”#26B2B6″ global_colors_info=”{}”][et_pb_blurb image=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2023\/07\/AviadoBio-icon-FTD-5.png” alt=”Aviadobio” icon_placement=”left” image_icon_width=”100px” content_max_width=”100%” icon_placement_tablet=”” icon_placement_phone=”top” icon_placement_last_edited=”on|phone” _builder_version=”4.16″ _module_preset=”default” header_text_color=”#ffffff” header_font_size=”26px” header_letter_spacing=”2px” body_text_color=”#43464F” body_font_size=”20px” body_link_font=”SweetSans Light||||||||” body_link_text_color=”#26B2B6″ body_link_font_size=”18px” body_link_letter_spacing=”3px” image_icon_custom_padding_tablet=”” image_icon_custom_padding_phone=”” image_icon_custom_padding_last_edited=”on|phone” custom_css_blurb_image=”padding-right:20px;||” border_color_all_image=”#26B2B6″ border_width_all_image_tablet=”” border_width_all_image_phone=”” border_width_all_image_last_edited=”on|phone” image_max_width=”100px” global_colors_info=”{}” body_link_text_color__hover_enabled=”off|desktop” body_link_text_color__hover=”#ffffff”]<\/p>\n

Circa 11.000 persone negli Stati Uniti ed in EU5 convivono con la FTD-GRN e si stima che ogni anno vengano confermati 2.000 nuovi casi.\u00b9\u02d2\u00b9\u00b9<\/span><\/p>\n

[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”||40px||false|false” border_width_bottom=”2px” border_color_bottom=”#26B2B6″ global_colors_info=”{}”][et_pb_blurb image=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2023\/07\/AviadoBio-icon-FTD-6.png” alt=”Aviadobio” icon_placement=”left” image_icon_width=”100px” content_max_width=”100%” icon_placement_tablet=”” icon_placement_phone=”top” icon_placement_last_edited=”on|phone” _builder_version=”4.16″ _module_preset=”default” header_text_color=”#ffffff” header_font_size=”26px” header_letter_spacing=”2px” body_text_color=”#43464F” body_font_size=”20px” body_link_font=”SweetSans Light||||||||” body_link_text_color=”#26B2B6″ body_link_font_size=”18px” body_link_letter_spacing=”3px” image_icon_custom_padding_tablet=”” image_icon_custom_padding_phone=”” image_icon_custom_padding_last_edited=”on|phone” custom_css_blurb_image=”padding-right:20px;||” border_color_all_image=”#26B2B6″ border_width_all_image_tablet=”” border_width_all_image_phone=”” border_width_all_image_last_edited=”on|phone” image_max_width=”100px” global_colors_info=”{}” body_link_text_color__hover_enabled=”off|desktop” body_link_text_color__hover=”#ffffff”]<\/p>\n

Attualmente, per i soggetti affetti da FTD, non sono disponibili trattamenti modificanti la malattia.<\/p>\n

[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=”on|phone” _builder_version=”4.24.2″ _module_preset=”default” custom_padding=”60px||0px||false|false” custom_padding_tablet=”” custom_padding_phone=”0px||0px||true|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_toggle title=”RIFERIMENTI BIBLIOGRAFICI” closed_toggle_text_color=”#43464F” icon_color=”#26B2B6″ open_icon_color=”#26B2B6″ disabled_on=”off|off|off” _builder_version=”4.22.1″ _module_preset=”default” title_level=”h2″ title_font_size=”24px” title_letter_spacing=”1px” body_font_size=”16px” text_orientation=”left” custom_padding_tablet=”” custom_padding_phone=”||||false|true” custom_padding_last_edited=”on|phone” title_font_size_phone=”20px” title_font_size_last_edited=”off|desktop” border_width_all=”0px” border_color_all=”#E5E5E5″ global_colors_info=”{}”]<\/p>\n

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    Storie degli accompagnatori familiari o professionali dal percorso FTD<\/h2>\n

    La diagnosi di demenza frontotemporale: l\u2019esperienza diretta di familiari, dalla diagnosi alla progressione della malattia nelle persone care affette da FTD.<\/p>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.25.1″ _module_preset=”default” max_width=”1200px” custom_margin=”||||false|false” custom_padding=”0px||0px||false|false” animation_style=”fade” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.25.1″ _module_preset=”default” background_color=”#43464F” global_colors_info=”{}”][et_pb_video _builder_version=”4.24.2″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” title_text=”Screenshot 2025-04-08 at 09.51.09″ src=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2025\/04\/katie_brandt_-_long-form_video_-_9.12.24_-_final-720p.mp4″ image_src=”https:\/\/quizzical-yonath.213-158-90-7.plesk.page\/wp-content\/uploads\/2025\/04\/Screenshot-2025-04-08-at-09.51.09.png” sticky_enabled=”0″][\/et_pb_video][et_pb_text _builder_version=”4.25.1″ _module_preset=”default” text_text_color=”#ffffff” header_font=”||||||||” header_text_color=”#ffffff” header_font_size=”34px” header_letter_spacing=”2px” header_line_height=”1.4em” header_2_font=”|||on|||||” header_2_text_color=”#43464F” header_2_font_size=”28px” header_2_letter_spacing=”2px” header_2_line_height=”1.4em” header_3_font=”|||on|||||” header_3_text_color=”#ffffff” header_3_letter_spacing=”2px” header_3_line_height=”1.2em” background_color=”#43464F” custom_margin=”20px||||false|false” custom_padding=”20px|20px|20px|20px|false|true” header_2_font_size_tablet=”” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n

    KATIE: ESPERTO, SOSTENITORE ED EDUCATORE IN MATERIA DI DEMENZA<\/h3>\n

    Katie \u00e8 diventata un\u2019assistente quando al marito \u00e8 stata diagnosticata la FTD alla giovane et\u00e0 di 29 anni. Scoprite di pi\u00f9 sull’esperienza di Katie che sostiene suo marito dalla sua diagnosi di FTD, il tutto con un figlio piccolo da crescere e con la sua dedizione a promuovere la consapevolezza e supportare le famiglie colpite da questa devastante malattia neurodegenerativa.<\/p>\n

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    Jacquelyn: Esperienza dell\u2019impatto della malattia dal punto di vista di una figlia<\/h3>\n

    I sintomi di FTD della madre di Jacquelyn sono iniziati gi\u00e0 nel 2013 con insonnia, perdita di memoria e differenze nel suo comportamento abituale. Il video di Jacquelyn mentre racconta l\u2019esperienza di sua madre con la FTD e come la sua famiglia sta affrontando insieme questa malattia devastante.<\/p>\n

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    Tanya: Esperienza dell\u2019impatto della malattia dal punto di vista di una moglie<\/h3>\n

    Il marito di Tanya era un compagno amato, un padre amato e un insegnante di storia delle scuole superiori, <\/span>deceduto<\/span> cinque anni dopo la diagnosi di FTD. Scopri di pi\u00f9 sulla diagnosi di FTD, sul ruolo di Tanya come suo accompagnatore familiare o professionale e sulla sua missione di aumentare la consapevolezza sulla FTD.<\/span><\/p>\n

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    Esperienza dell\u2019impatto della malattia dal punto di vista di una figlia<\/h3>\n

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